Freitag 21. Juni 2013, 13:51
Alcohol and Alcoholism Vol. 46, No. 4, p. 503, 2011
doi: 10.1093/alcalc/agr058
LETTER TO THE EDITOR
Baclofen: What’s in a Word? A World of Difference O. Ameisen
Ameisens Replik auf eine Bemerkung von Addolorato :
"The paper by Addolorato et al. (2011) attributes to me and
to Dr William Bucknam a hypothesis that neither of us has
advanced. Addolorato et al. write:
‘However, anecdotal reports have hypothesized the ability
of high doses of baclofen (up to 140 and 270 mg/day) to
reduce alcohol craving and consumption (Ameisen, 2005a;
Bucknam, 2007)’.
My 2005 paper and Bucknam’s (2007) paper expressly
advance a very different hypothesis, that
baclofen at higher
doses can suppress, which is to say, eliminate, alcohol
craving and uncontrolled alcohol consumption. To reduce
something is to moderate it. To suppress something is to
prevent or stop it. This semantic difference is a difference of
kind, not degree. "
Wer hat wohl Recht?
Liebe Grüße
Werner