Medscape Medical News, Nov 12, 2010
Baclofen Can Ease Symptoms of Acute Alcohol WithdrawalBob Roehr
...This study confirms what has been seen in other studies with similar but not identical designs. Still, "it is too early to advise physicians to use baclofen for treating AWS," Dr. Leggio said.
Industry is not interested in funding research on a generic drug, so support must come from the National Institutes of Health and from other foundations, he noted.
Dr. Leggio said baclofen is very safe to use in patients with liver disease because it is primarily metabolized through the kidneys, unlike alternative drugs for alcohol dependency that are metabolized in the liver and are contraindicated for patients with cirrhosis.